100% natural feed supplement for horses with mastic, inulin and beta-glucans

MasticVital HORSE is a highly specialized natural feed supplement in the form of a loose mixture, specially formulated for horses. The product is based on three key ingredients: mastic (natural resin from Pistacia lentiscus var. chia), inulin (prebiotic fiber from chicory) and beta-glucans (polysaccharides from the yeast Saccharomyces cerevisiae). The recommended dosage is precisely set at 1.6 g per 100 kg of live weight per day, which for an average horse weighing 500 kg represents approximately 8 grams per day.

MASTICH, INULIN AND BETA-GLUCAN IN THE CARE OF THE DIGESTIVE SYSTEM OF HORSES

MasticVital HORSE is a triad of natural substances with complementary effects on the horse's digestive system. Each substance targets a different level of protection, creating a comprehensive preventive and therapeutic system.

MASTIC (CHIOS MASTIC)
- Resin from the Pistacia lentiscus tree from the island of Chios
- Active components: α-terpineol, methyl isoeugenol, triterpenes
- Essential oils with antibacterial properties

5 pillars of action:
1. Physical protection - Creates an adhesive film on the gastric mucosa, acts as
"biological patch"
2. Antimicrobial effect - Destroys pathogenic bacteria
3. Acidity regulation - Reduces the free acidity of gastric juices
4. Regenerative potential - Supports the restoration of damaged epithelial cells
5. Anti-inflammatory effect - Suppresses inflammatory processes in the mucous membrane

Practical significance:
- Direct prevention of gastric ulcers in horses
- Acceleration of healing of existing lesions

INULIN
- Fructooligosaccharide - prebiotic
- Sources: chicory, Jerusalem artichoke, agave
- Fermentable in the large intestine, indigestible in the small intestine

6 levels of action:

1. Selective microbiota nutrition - Supports the growth of Bifidobacterium and Lactobacillus
   2. Production of SCFA (short chain fatty acids) - Butyrate, propionate, acetate
   as an energy substrate
   for colonocytes
   3. Strengthening the intestinal barrier - Prevention of "leaky gut syndrome"
   4. Immunomodulation - 70% of the immune system resides in the intestines
   5. pH regulation - Slight acidification unfavorable for pathogens
   6. Improved mineral absorption - Increased absorption of Ca, Mg

Practical significance:
- Prevention of colic and diarrhea
- Stabilization of microbiota during stress
- Indirect protection of the entire GI tract
- Preventive action against dysbiosis

BETA-GLUCAN
- Polysaccharides with β-1,3 and β-1,6 glycosidic bonds
- Sources: yeast (Saccharomyces cerevisiae), mushrooms, cereals
- Immunomodulators recognized by pattern-recognition receptors

8 mechanisms of action:
1. Activation of immune cells - Stimulation of macrophages, neutrophils, dendritic cells
cells
2. Phagocytosis - Increased ability to eliminate pathogens
3. Cytokine cascade - Production of IL-1, IL-6, TNF-α for coordinated immune response
response
4. Physical protection - Formation of a viscous layer in the small intestine
5. Tissue regeneration - Acceleration of mucous membrane healing
6. Anti-inflammatory action - Regulation of excessive inflammatory response
7. Antioxidant activity - Reduction of oxidative stress
8. Glycemic stabilization - Slowing glucose absorption

Practical significance:
- Overall immunomodulation
- Support during recovery
- Prevention of infections in horses
- Excellent synergistic effect with other ingredients of the MasticVital product
HORSE

SYNERGIC EFFECT - KEY COOPERATION OF INGREDIENTS

Three-level protection:
1. MASTICHA → Stomach (gate of entry) - direct physical and biochemical protection
2. INULIN → Intestine (middle segment) - microbial homeostasis
3. BETA-GLUCAN → Entire GI tract - immune and regeneration support

KEY HEALTH BENEFITS
1. Comprehensive support for the digestive system
- Ensures stomach comfort and healthy digestion
- Especially important for horses exposed to stress and changes in feed ration
- Supports the regeneration and protection of the gastric and intestinal mucosa
2. Optimizing the gut microbiome
- The prebiotic effect of inulin selectively promotes the growth of beneficial
bacteria (especially Bifidobacterium)
- Creates a favorable intestinal environment
- Production of short fatty acids (butyric, propionic, acetic)
essential for the health of the intestinal mucosa
3. Strengthening natural immunity
- Beta-glucans activate immune cells (macrophages, neutrophils)
- Improves the body's ability to respond to pathogens and stress
- They function as biological modifiers of the immune response
4. Regeneration and protection under stress
- Supports recovery after physical exertion, stress or illness
- Reduces the negative effects of changes in feed ration, transport and racing
loads
- Ideal for sports horses and horses in recovery
5. Better nutrient utilization
- Harmonization of the intestinal environment leads to more efficient absorption
nutrients
- Improved fitness, energy and overall vitality
- Optimization of nutritional intake from the regular feed ration

MECHANISM OF ACTION OF INDIVIDUAL INGREDIENTS

➢ Mastic
- Provides natural protection of the gastric and intestinal mucosa
- Acts against pathogenic bacteria and microorganisms
- Supports the regeneration and healing of mucosal tissues 4
- Comes from the island of Chios (highest quality)
➢ Inulin
- Prebiotic fiber that supports the growth of beneficial bacteria
- Fermentation in the large intestine produces short-chain fatty acids
- Provides energy to colonocytes
- Maintains optimal pH in the intestinal environment
➢ Beta-glucans
- Purified 1,3/1,6-β glucans from yeast
- Activate the natural immune response
- Stimulate macrophages and neutrophils
- Improves the speed and efficiency of response to stressful situations

PRACTICAL INSTRUCTIONS FOR USE

❖ Dosage
- 1.6 g per 100 kg of live weight per day
- Horse 500 kg = 8 g per day
- Served mixed into food, ideally in the evening
- Allows for optimal processing during night rest
❖ Feeding length
- Minimum 4-6 weeks for full effect
- First positive changes: 1-2 weeks
- Optimal effect: after 4-6 weeks
- Suitable for long-term continuous administration
❖ Available packages
- 250 g – one-month package (for a horse weighing 500 kg)
- 500 g – two-month package (more economical)
- 1 kg – four-month package (the most economical option)

SAFETY AND TOLERANCE

★ Security profile
- No known side effects when following the dosage
- FEI-compatible – suitable for sport horses (no banned substances)
- Not on the International Equestrian Federation's list of doping substances
- Highly tolerated by the horse's body

★ Possible adaptive responses
- In more sensitive individuals, slight changes in stool consistency are possible when
first administration
- Solution: divide the daily dose into two smaller portions
- This is a natural adaptation of the intestinal microflora
- Temporary phenomenon that resolves within a few days

★ Important notices
- Not a substitute for a balanced diet
- Does not replace veterinary care
- Do not exceed the recommended dosage.
- Store in a dry place, protect from heat and light

QUALITY AND PRODUCTION STANDARDS

● Raw material quality
- Mastic from the island of Chios (the highest world quality)
- Food or pharmaceutical grade inulin
- Purified beta-glucans from Saccharomyces cerevisiae
- Guaranteed content of active ingredients

● Production process
- Manufactured in the EU under GMP (Good Manufacturing Practice) regime
- Each batch tested for purity and microbiological parameters
- Highest standard of quality and safety
- Consistent product quality

● Combination with other accessories
- Synergistic effect with probiotics – prebiotic inulin supports live 6
probiotic cultures
- Compatible with vitamins and minerals – no risk of adverse interactions
- Recommended consultation with a veterinarian for comprehensive supplementation

IDEAL INDICATIONS FOR USE

Horses with digestive problems – supporting stomach and intestinal comfort
Sport horses – managing racing stress and strain
Horses after illness – support for recovery
When changing feed - mitigating negative effects
During transport – reduction of stress response
Prevention – long-term support of health and vitality
Horses with weakened immunity – strengthening defenses

KEY PRODUCT BENEFITS

✓ Natural composition without synthetic additives, hormones or banned substances
✓ Triple mechanism of action – digestion, microbiome, immunity
✓ Scientifically proven formulation based on the latest findings
✓ Easy to administer – loose mixture for feeding
✓ Accurate dosage according to the horse's weight
✓ Safe for sport horses – FEI-compliant
✓ Suitable for long-term use without the risk of side effects
✓ Flexible packaging – three options to suit your needs
✓ European quality – production in GMP mode

SUMMARY - MOST IMPORTANT POINTS

★ 1. Multimodal approach is more effective than monotherapy
★ 2. Mastic = unique physical protection of the stomach
★ 3. Inulin = the basis of a healthy microbiota and intestinal barrier
★ 4. Beta-glucans = immunomodulation of the whole organism
★ 5. Natural substances with minimal side effects 7
★ 6. Scientifically based mechanisms (although partly from human medicine)
★ 7. Prevention and therapy - universal use
★ 8. Synergistic effect - sum > individual parts
★ 9. Safe long-term use - suitable for continuous supplementation
★ 10. Comprehensive protection of the entire digestive tract from the stomach to the colon

MasticVital HORSE is a comprehensive, science-based solution for supporting equine health, focusing on three key areas: the digestive system, the gut microbiome and the immune system. The unique combination of mastic, inulin and beta-glucans provides a synergistic effect that brings demonstrable results after just a few weeks of use.
The product is an ideal choice for responsible breeders and owners who prefer a natural, safe and effective approach to supporting the health of their horses. The high quality of raw materials, strict manufacturing standards and the absence of banned substances make MasticVital HORSE a trusted supplement suitable for both recreational and sport horses at all performance levels.